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FROM LITTLE ROCK - ARKANSAS I-40 west to Conway, AR to intersection with US 65 North US 65 North through Harrison, AR to intersection with US 62 West US 62 West to Eureka Springs to intersection with Arkansas 23 North Through town on 23 N to Eureka Springs and Northwest Arkansas Train Depot At Train Depot turn left and make an immediate left onto Hillside Ave. Proceed up Hillside Ave about 250 yards; veer right at Arsenic and Old Lace sign into driveway.
FROM ST. LOUIS - MISSOURI I-44 West to Springfield, MO to intersection with US 65 South US 65 South towards Harrison, AR to intersection with US 62 West US 62 West to Eureka Springs to intersection with Arkansas 23 North Through town on 23 N to Eureka Springs and Northwest Arkansas Train Depot At Train Depot turn left and make an immediate left onto Hillside Ave. Proceed up Hillside Ave about 250 yards; veer right at Arsenic and Old Lace sign into driveway
FROM KANSAS CITY -KANSAS OR MISSOURI US 71 South through MO to Rogers, AR to intersection with US 62 East Turn left onto US 62 East to Eureka Springs, AR to intersection with Arkansas 23 North Through town on 23 N to Eureka Springs and Northwest Arkansas Train Depot At Train Depot turn left and make an immediate left onto Hillside Ave. Proceed up Hillside Ave about 250 yards; veer right at Arsenic and Old Lace sign into driveway.
FROM TULSA -OKLAHOMA US 412 through Springdale, AR to intersection with Arkansas 45 North Turn left onto Arkansas 45 North to intersection with Arkansas 12 East Turn right onto Arkansas 12 East to the intersection with Arkansas 23 North Turn left onto 23 North to Eureka Springs At the intersection of 23 N and US 62 turn left, stay on 62 W/ 23N until 23N leaves US 62. Turn right towards downtown Eureka Springs/Historic District Go through town to the Eureka Springs and Northwest Arkansas Train Depot At Train Depot turn left and make an immediate left onto Hillside Ave. Proceed up Hillside Ave about 250 yards; veer right at Arsenic and Old Lace sign into driveway.